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FACULTY

Dr. Vivek Keshri Assistant Professor

School of Applied Sciences

Dr. Vivek Keshri

Specialization

Bioinformatics data analysis- antibiotic resistance genes identification, differential expression profiling, next-generation sequencing data analysis

Programs Organised

Qualification

Ph.D.

Teaching Experience

7 Years

Publications In Refereed Journals

  • Human metallo-β-lactamase enzymes degrade penicillin

    Diene SM, Pinault L, Keshri V, Armstrong N, Khelaifia S, Chabrière E, Caetano-Anolles G, Colson P, La Scola B, Rolain JM, Pontarotti P, Raoult D. Sci Rep. 2019 Aug 21;9(1):12173. doi: 10.1038/s41598-019-48723-y. PMID: 31434986; PMCID: PMC6704141.

  • Promiscuous Enzyme Activity as a Driver of Allo and Iso Convergent Evolution, Lessons from the β-Lactamases

    Keshri V, Chabrière E, Pinault L, Colson P, Diene SM, Rolain JM, Raoult D, Pontarotti P. Int J Mol Sci. 2020 Aug 29;21(17):6260. doi: 10.3390/ijms21176260. PMID: 32872436; PMCID: PMC7504333.

  • Dual RNase and β-lactamase Activity of a Single Enzyme Encoded in Archaea

    Diene SM, Pinault L, Armstrong N, Azza S, Keshri V, Khelaifia S, Chabrière E, Caetano-Anolles G, Rolain JM, Pontarotti P, Raoult D. Life (Basel). 2020 Nov 14;10(11):280. doi: 10.3390/life10110280. PMID: 33202677; PMCID: PMC7697635.

  • Phylogenomic Analysis of β-Lactamase in Archaea and Bacteria Enables the Identification of Putative New Members.

    Keshri V, Panda A, Levasseur A, Rolain JM, Pontarotti P, Raoult D. Genome Biol Evol. 2018 Apr 1;10(4):1106-1114. doi: 10.1093/gbe/evy028. PMID: 29672703; PMCID: PMC5905574.

  • The functional convergence of antibiotic resistance in β-lactamases is not conferred by a simple convergent substitution of amino acid.

    Keshri V, Arbuckle K, Chabrol O, Rolain JM, Raoult D, Pontarotti P. Evol Appl. 2019 Jul 18;12(9):1812-1822. doi: 10.1111/eva.12835. PMID: 31548859; PMCID: PMC6752183.

  • An Integrative Database of β-Lactamase Enzymes: Sequences, Structures, Functions, and Phylogenetic Trees.

  • Keshri V, Diene SM, Estienne A, Dardaillon J, Chabrol O, Tichit L, Rolain JM, Raoult D, Pontarotti P. Antimicrob Agents Chemother. 2019 Apr 25;63(5):e02319-18. doi: 10.1128/AAC.02319-18. Print 2019 May. PMID: 30783007

Other Publications

  • Structure Prediction and Binding Site Analysis of Hepatotoxic Microcystin-LR Degrading MlrC-Like Protein

    from Burkholderia sp. using Computational Approaches

    Singh DP, Prabha R, Keshri V, and Abhilash PC

    2016, Current Research in Bioinformatics

  • Genome subtraction for the identification of potential antimicrobial targets in Xanthomonas oryzae pv

    oryzae PXO99A pathogenic to rice

    Keshri V, Singh DP, Prabha R, Rai A, and Sharma AK. 2013, 3Biotech (Springer) [PMID: 28324466]

Research Project

Bioinformatics data analysis- Antibiotic resistance beta-lactamase gene identification from different domain of life such as bacteria, archaea, eukaryotes along with metagenomes,

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