Biotechnology Research Institute in Bangalore, India - REVA University
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School of Applied Sciences of REVA University is Organizing a Two day “International Conference on Recent Advances in Applied Sciences” during 17th -18th October 2019 (ICRAAS2019)The British Deputy High Commission Bengaluru has announced that the Chevening Scholarships & Fellowships is now accepting applications, all students can approach and also apply on
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Research in Biotechnology Program in India - REVA Universtiy
Research in Biotechnology

Research in Biotechnology

List of Guides & their expertise

PhD Guides & Candidates List-School of Bio Technology
2014 Batch
Sl No Registration Number Name of the Candidate Name of the Internal Guide 
1 R14PBT01 Rayasam Vijay Dr.Tarika Kumar
2 R14PBT02 B. Kiran Kumar Dr. K M Kumar
3 R14PBT03 Ishwar Chandra Dr. K M Kumar
4 R14PBT04 Siva Baludu Dr. Aruna J
5 R14PBT05 Supriya S. Doijode Dr.P.Sridhar Reddy
6 R14PBT06 Shilpa R Raju Dr. Aruna J
2015 Batch
Sl No Registration Number Name of the Candidate Name of the Internal Guide 
1 R15PBT01 Aamir Javed Dr. Manjula K R
2 R15PBT02 Ashwini L S  Dr. Ramesh N
3 R15PBT03 Nisha Rajasekhar Dr. Sridhar Reddy
4 R15PBT04 Proma Chakraborty Dr. K M Kumar
2016 Batch
Sl No Registration Number Name of the Candidate Name of the Internal Guide 
1 R16PBT01 Mallikarjuna Pulipeta Dr. Raghavendra PB
2 R16PBT02 Sharmistha Dutta Dr. Ramesh N
3 R16PBT03 Prashanth Kumar H P Dr. Ramesh N
4 R16PBT05 Anupam J Das Dr. Ramesh N
2017 Batch
Sl No Registration Number Name of the Candidate Name of the Internal Guide 
1 R17PBT01 Pooja Biswas Dr. Raghavendra PB
2 R17PBT02 Shilpa B R Dr. Ramesh N
3 R17PBT03 Renuka Ravinath Dr. Ramesh N
2018 Batch
Sl No Registration Number Name of the Candidate Name of the Internal Guide
1 R18PBT01 Latha Maheshwari G Dr. Ramachandra. R
2 R18PBT02 Sivaramireddy Bhavanam Dr. Ramachandra. R
2019 Batch
Sl No Registration Number Name of the Candidate Name of the Internal Guide
1 R19PBT01 Shanmugam V M Dr. Manjula K R
2 R19PBT02 Chethan Kumar N Dr. N M Guruprasad
3 R19PBT03 Apsara V Dr. N M Guruprasad
4 R10PBT04 Khushbu Nishad Dr. N Ramesh

List of guides in REVA University

Sr. No Name
1 Dr. Manjula K R
2 Dr. Ramachandra R
3 Dr. Guruprasad N M

Faculty members pursuing PhD

Sr. No Name University Date of registration

Prof Shilpa B R

REVA University

 June 2017


Prof Renuka Madhu

REVA University

June 2017

Research Facilities

State-of-the-art clean rooms & well set laboratory facilities.
Well equipped PG labs, UG labs, Plant tissue culture lab (PTC), Clean room for Animal cell culture (ATC) and a research lab to facilitate research activities for students as well as for faculty.
Department has all the major instruments like PCR, UV-Spectrophotometer, Electrophoretic units, Digital photoelectric colorimeter, ELISA reader, Microscopes, CO2 incubator, Millipore water purification system, High speed microcentrifuges,Deep freezers (-20°c / -80°c).
Short and long term in-house projects to UG/PG students and faculty to improve research ability and practical skills.

Research Grants

Ms Sridevi, Mr Nalini Prasad, Dr Vidyawati VGST-SPICE Biomonitoring of lake waters using Daphnia acute toxicity test 2011-2012
Mr.Pavan, Mr.Milan, Mr.Sunil Sapkota VGST-SPICE Biodegradation of coir pith by white rot fungi for production of biofuel 2011-2012

Research Publications

  • Karthikeyan M, Govindarajan R, Duraisamy E, Veena V, Sakthivel N, Manimaran B Self-assembly of chalcogenolato-bridged ester and amide functionalized dinuclear re(I) metallacycles: synthesis, structural characterization and preliminary cytotoxicity studies. Chemistry Select 2017(2), 3362 – 3368.
  • Suresh AK, Veena V, Hameed BS, Ramasamy S, Sakthivel N. Medium constituents mediated engineering for size and shape tuning of gold nanocrystallites. Journal of Industrial and Engineering Chemistry, 2017 (15): 288-294.
  • Haleel A, Mahendiran D, Veena V, Sakthivel N, Rahiman AK. Antioxidant, DNA interaction, VEGFR2 kinase, topoisomerase I and in vitro cytotoxic activities of heteroleptic copper(II) complexes of tetrazolo[1,5-a]pyrimidines and diimines. Material Science and Engineering: C 2016: 366-382
  • Govindarajan R, Nagarajaprakash R, Veena V, Sakthivel N, Manimaran B. One-pot reaction of amide functionalized Re(I) based dinuclear metallacycles: Synthesis, characterization and evaluation for anticancer potential. Polyhedron 2017: xxx, xxx–xxx.
  • Veena V, Kennedy RK, Lakshmi P, Krishna R, Sakthivel N. Anti-leukemic, anti-lung and antibreast cancer potential of the microbial polyketide, 2,4-diacetylphloroglucinol (DAPG) and its interaction with the metastatic proteins than the antiapoptotic Bcl-2 proteins. Molecular and Cellular Biochemistry 2016: 1-10.
  • Veena V, Popavath PR, Kennedy RK, Sakthivel N. In vitro antiproliferative, proapoptotic, antimetastatic and anti-inflammatory potential of 2,4-Diacteylphloroglucinol (DAPG) by Pseudomonas aeruginosa strain FP10. Apoptosis 2015: 20(10), 1281-95.
  • Ramakrishna B, Nagaraja PR, Veena V, Sakthivel N, Manimaran B. Self-assembly of oxamidato bridged ester functionalised dirhenium metallastirrups: synthesis, characterisation, and cytotoxicity studies. Dalton Transactions 2015: 44, 17629-39.
  • Kennedy RK, Naik PR, Veena V, Lakshmi BS, Lakshmi P, Krishna R, Sakthivel N. 5-Methyl phenazine-1-carboxylic acid: A novel bioactive metabolite by a rhizosphere soil bacterium that exhibits potent antimicrobial and anticancer activities. Chemico-Biological Interactions 2015: 231, 71-82
  • Kennedy RK, Veena V, Naik PR, Lakshmi P, Krishna R, Sudharani S, Sakthivel N. Phenazine-1- carboxamide (PCN) from Pseudomonas sp. strain PUP6 selectively induced apoptosis in lung (A549) and breast (MDA MB-231) cancer cells by inhibition of antiapoptotic Bcl-2 family proteins. Apoptosis 2015: 20, 858–868.
  • Haleel A, Arthi P, Dastagiri RN, Veena V, Sakthivel N, Arun Y, Perumal A, Kalilur Rahiman A. DNA binding, molecular docking and apoptotic inducing activity of nickel(II), copper(II) and zinc(II) complexes of pyridine-based tetrazolo[1,5-a]pyrimidine ligands. RSC Advances 2014: 4, 60816-60830.
  • Kumar AC, Karthikeyan S, Varghese B, Veena V, Sakthivel N, Manimaran B. Synthesis, characterisation and cytotoxicity evaluation of rhenium(I) based ester functionalised dinuclear metallacyclophanes. Journal of Organometallic Chemistry 2014: 766, 86-94.
  • Kumar AC, Nagarajaprakash R, Victoria W, Veena V, Sakthivel N, Manimaran B. Synthesis, characterisation and cytotoxicity studies of manganese(I) and rhenium(I) based metallacrown ethers containing pyridine appended bidentate ligand. Inorganic Chemistry Communications 2016: 64, 39–44.
  • Lalitha P, Veena V, Vidhyapriya V, Lakshmi P, Krishna R, Sakthivel. N. Anticancer potential of pyrrole (1, 2, a) pyrazine 1, 4, dione, hexahydro 3-(2-methyl propyl) (PPDHMP) extracted from a new marine bacterium, Staphylococcus sp. strain MB30. Apoptosis 2016 21(15) 566–577
  • Lakshmi P, Kumar A, Veena V, Sakthivel N, Krishna R Identification of Natural Allosteric Inhibitor for Akt1 Protein through Computational Approaches and in vitro Evaluation. International Journal of Biological Macromolecules Volume 96, March 2017, Pages 200-213
  • Renuka Madhu, Anupam J Das, Laxmikanth, G. and Veena, V. Established Chonemorpha fragrans callus exhibited biological activities as that of plant extract. International Journal of Current Research 2017 9(2): 46545-46552.
  • BB Xavier, Anupam J Das, Guy Cochrane, Sandra De Ganck, S Kumar-Singh, FM Aarestrup, H Goossens, S Malhotra-Kumar. Consolidating and exploring antibiotic resistance gene data resources. Journal of Clinical Microbiology 2016: 54(4), 851-859
  • S Malhotra-Kumar, BB Xavier, Anupam J Das, C Lammens, HTT Hoang, NT Pham, H Goossens. Colistin-resistant Escherichia coli harbouring mcr-1 isolated from food animals in Hanoi, Vietnam. The Lancet Infectious Diseases 2016:16(3), 286-287
  • S Malhotra-Kumar, BB Xavier, Anupam J Das, C Lammens, P Butaye, H Goossens. Colistin resistance gene mcr-1 harboured on a multidrug resistant plasmid. The Lancet Infectious Diseases 2016:16(3), 283-284
  • K Voordeckers, J Kominek, Anupam J Das, A Espinosa-Cantú, D De Maeyer, A Arslan, M Van Pee, Elisa van der Zande, W Meert, Y Yang, B Zhu, K Marchal, A DeLuna, V Van Noort, R Jelier, KJ Verstrepen. Adaptation to high ethanol reveals complex evolutionary pathways. PLoS Genetics 2015: 11(11), e1005635; +equal contribution
  • Anupam J Das, BB Xavier, G Cochrane, S De Ganck, S Kumar-Singh, FM Aarestrup, H Goossens, S Malhotra-Kumar (2016) Effective use of antibiotic resistance gene databases for whole genome and metagenomic sequencing data. ECCMID, April 9-12, Amsterdam, The Netherlands.
  • Ramya M & Shivakameshwari M. N, Genome size estimation in aneuploid accessions of Urginea indica Kunth. Hyacinthaceae, Int. J. Pure App. Biosci. 4 (4): 93-101 (2016)
  • Ramya M, M N Shiva kameshwari & K J TharaSaraswathi, A study of genetic diversity in different accessions of Urginea species Hyacinthaceae, as revealed by ISSR. IJCR, 9 (06): 52450-52453 (2017)
  • Pradeep S. Kaushik, Ramya. M, Gargi G P; Mitodepressive activity of two common food dyes on Allium cepa L. root meristem, IJRASET, Volume 5 (9): 954-967 (2017)
  • Manjula. K. R, Intermittent cold-induced hippocampal oxidative stress is associated with changes in the plasma lipid composition and is modifiable by vitamins C and E in old rats. Neurochemistry international, 13: 74C:46-52 (2014). IF 2.659
  • P.P. Sengupta., G.R. Rudramurthy, M. Ligi, M. Roy, V. Balamurugan, P. Krishnamoorthy, M. Nagalingam, L. Singh. and H. Rahman. (2014). Sero- Diagnosis of surra exploiting recombinant VSG antigen based ELISA for Surveillance. Veterinary Parasitology. 205: 490-498. Impact Factor: 2.46
  • M. Ligi., P. P. Sengupta., G. R. Rudramurthyand H. Rahman. (2016). Flagellar antigen based CI-ELISA for sero-surveillance of surra. Veterinary Parasitology. 219: 17–23. Impact Factor: 2.46
  • P. Krishnamoorthy., P.P. Sengupta., Sangita Das., M. Ligi., B.R. Shome., H. Rahman. (2016). Cytokine gene expression and pathology in mice experimentally infected with different isolates of Trypanosoma evansi. Experimental Parasitology. 170: 168-176. Impact Factor: 1.623
  • G.R Rudramurthy, P.P Sengupta, M. Ligi, H. Rahman (2017). An inhibition enzyme immuno assay exploring recombinant invariant surface glycoprotein and monoclonal antibodies for surveillance of surra in animals. Biologicals. 46, 148-152. Impact Factor: 1.69
  • Ligi Jose., Sengupta P. P., Rudramurthy G. R and Rahman. H (2015). A pilot sero-survey for surra in livestock in Karnataka by ELISA using flagellar antigen of Trypanosoma evansi. International Journal of fundamental and applied sciences. 4: 99-103
  • Ligi Jose., Sengupta P. P., Rudramurthy G. R and Rahman. H (2016). Seroprevalence of surra in camels using flagellar antigen in some areas of Rajasthan: A pilot survey International Journal of fundamental and applied sciences. 5: 23-26
  • Rudramurthy, G.R., Sengupta, P.P., Lakkundi, J.N., Ligi, M., D’Souza, P.E., and Rahman, H. (2014). Sequencing and analysis of invariant surface glycoprotein (ISG) gene from Trypanosoma evansi dog isolate. Research in Biotechnology. 6: 1-9.
  • Rudramurthy, G.R., Sengupta, P.P., Ligi, M., Balamurugan, V., Suresh K.P and Rahman, H. (2017). Serodiagnosis of animal trypanosomosis using a recombinant invariant surface glycoprotein of Trypanosoma evansi. Indian Journal of Experimental Biology. 55: 209-216. Impact Factor: 1.165
  • P.P. Sengupta., M. Ligi., G.R. Rudramurthy., V. Balamurugan and H. Rahman. (2016). Development of ELISA exploring recombinant variable surface glycoproteinfor diagnosis of surra in animals. Current Science. 111(12), 2022-2027. Impact Factor: 0.9
  • Durairaj Sekar, Shilpa B.R, Anupam J Das; Relevance of microRNA 21 in Different Types of Hypertension; Curr Hpertens Rep. 2017 Jul:19(7):57
  • Prakash G. Patil , M. Byre Gowda, Ikechukwu O. Agbagwa, Khela Ram Soren, R. Ramachandra and H. E. Shashidhar 2015. Molecular diversity study using SSAP MARKERS in pigeonpea (Cajanus cajan L. Millsp.).The Bioscan 10(4): 1915-1920.
  • S L Krishnamurthy, Y Prashanth , A Mohan Rao , K Madhavi Reddy And R Ramachandra 2015. Assessment of AFLP marker based genetic diversity in chilli (Capsicum annuum L. & C. baccatum L.). Indian Journal of Biotechnology Vol 14, January 2015, pp 49-54
  • Ramachandra, R., Kumar. V., Ramanjini Gowda, P. H., Pramila, C. K And Ganapathy, K. N. Biolistic mediated transformation and transient β-1,3glucuronidase expression in Indica rice variety Mangala. J. Bioinfolet. Vol 11 No 1 ( Jan - Mar 2014)
  • N.M.Guruprasad, N.N.MohanKumar, S.K.Jalali and H.P.Puttaraju. 2017. Wolbachia and Phage WO infection in agriculturally important insects. International Journal of Entomology  Research. 2(5):36-39
  • N.M.Guruprasad, B.M.Harish, S.K.Jalali and H.P.Puttaraju. 2015.Characterization of Wolbachia cell division protein (ftsz) gene for potential management of Uzifly Exorista sorbillans (Diptera: Tachinidae). Journal of Entomology and Zoology Studies. 3 (2): 57-61.
  • N.M.Guruprasad, B.M.Harish, S.K.Jalali and H.P.Puttaraju. 2014. Insilico modeling of Wolbachia and its potentials in combating mosquito borne diseases Chikungunya and Dengue. International Journal of Mosquito Research. 1 (3): 61-68.
  • N.M.Guruprasad and H.P.Puttaraju 2014. Cytoplasmic introgression and  diversity in Wolbachia infected uzifly Exorista sorbillans (Diptera:Tachinidae). Journal of Entomology and Zoology Studies.  2 (4): 42-50.
  • N. M. Guruprasad, S.K.Jalali and H.P.Puttaraju 2013. Wolbachia infection frequency and phylogenetic affiliationof Wolbachia cell division protein gene (ftsZ) in Uzi fly Exorista sorbillans (Diptera: Tachinidae) of Karnataka (India). Journal of Entomology and Zoology Studies. 1 (6):129-133
  • Sumithra, N. M. Guruprasad and H.P.Puttaraju 2013. Molecular detection of Wolbachia and phage WO infection in Spodoptera litura. (Lepidoptera: Noctuidae) Journal of Entomology and Zoology Studies 1 (4): 54-57
  • M.Shivashankar, N.M.Guruprasad and N.Chandan 2013. Heterogenetity in honeybee populations of India revealed by RAPD analysis. Journal of Chemical, Biological and Physical Sciences section B. 3(2):1115-1119.
  • N.M.Guruprasad and H.P.Puttaraju. 2013. Wolbachia- a potential tool to suppress Uzifly Exorista sorbillans a serious menace of Silkworm Bombyx mori.  Journal of Biological Control 27(1):24-28.
  • Sumithra, N.M. Guruprasad, and H.P. Puttaraju 2012. A Comparative analysis of Long PCR and Standard PCR technique in detecting the Wolbachia Endosymbiont. Current Trends in Biotechnology and Pharmacy. 6 (3): 381-388.
  • N.M. Guruprasad, Sumithra, L. Mouton and H.P. Puttaraju 2012. Long PCR : a sensitive PCR protocol for amplification of Wolbachia endosymbiont in Indian Honey Bees. Journal of Entomological Research. 36 (2): 119-122.
  • N.M. Guruprasad, L. Mouton and H.P. Puttaraju 2011. Effect of antibiotic,  temperature curing of Wolbachia and seasonal variation on the reproductive fitness of the Uzifly Exorista sorbillans (Diptera: Tachinidae. Symbiosis.  54:151–158. DOI 10.1007/s13199-011-0138-y
  • N.M. Guruprasad, L. Mouton, Sumithra and H.P. Puttaraju 2011. Survey of       Wolbachia and its Phage WO in the Uzifly Exorista sorbillans   (Diptera:Tachinidae). Current Microbiology. 63:267–272.  DOI 10.1007/s00284-011-9973-6.
  • Prakash.B.M, Guruprasad.N.M, Sumithra and H.P.Puttaraju. 2006. Effect of Albendazole on silkworm, Bombyx mori (Lepidoptera: Bombycidae). J Ecobiology  19(3): 239- 242.
  • Puttaraju.H.P, .Prakash.B.M, Sumithra and Guruprasad.N.M, 2005.Screening of natural essential oils for uzi fly management. Sericologia  54(4): 475-479
  • N.M. Guruprasad, S. K. Jalali and H. P. Puttaraju 2014. Wolbachia-a foe for Mosquitoes. Asian Pacific Journal of Tropical Diseases. 4(1):78-81. doi:10.12980/S2222-1808(14)60123
  • N.M.Guruprasad, S.K.Jalali and H.P.Puttaraju 2013. Wolbachia-a boon or bane for insects? Journal of Entomological Research. 37 (4): 351-358.
  • Mishra, P., Balaji, A.P.B., Swathy, J.S., Paari, A.L., Kezhiah, M., Tyagi, B.K., Mukherjee, A. and Chandrasekaran, N., 2016. Stability assessment of hydro dispersive nanometric permethrin and its biosafety study towards the beneficial bacterial isolate from paddy rhizome. Environmental Science and Pollution Research, 23(24), pp.24970-24982. (I.F – 2.8). ISSN: 0944-1344 (Print) 1614-7499 (Online)
  • Mishra, P., Jerobin, J., Thomas, J., Mukherjee, A. and Chandrasekaran, N., 2014. Study on antimicrobial potential of neem oil nanoemulsion against Pseudomonas aeruginosa infection in Labeo rohita. Biotechnology and applied biochemistry, 61(5), pp.611-619. (I.F – 1.44). ISSN:1470-8744
  • Mishra, P., Balaji, A.P.B., Dhal, P.K., Kumar, R.S., Magdassi, S., Margulis, K., Tyagi, B.K., Mukherjee, A. and Chandrasekaran, N., 2017. Stability of nano-sized permethrin in its colloidal state and its effect on the physiological and biochemical profile of Culex tritaeniorhynchus larvae. Bulletin of entomological research, 107(5), pp.676-688. (I.F – 1.78). ISSN: 0007-4853 (Print), 1475-2670 (Online)
  • Mishra, P., Tyagi, B.K., Chandrasekaran, N. and Mukherjee, A., 2018. Biological nanopesticides: a greener approach towards the mosquito vector control. Environmental Science and Pollution Research, 25(11), pp.10151-10163. (I.F – 2.8). ISSN: 0944-1344 (Print) 1614-7499 (Online)
  • Mishra, P., Samuel, M.K., Reddy, R., Tyagi, B.K., Mukherjee, A. and Chandrasekaran, N., 2018. Environmentally benign nanometric neem-laced urea emulsion for controlling mosquito population in environment. Environmental Science and Pollution Research, 25(3), pp.2211-2230. (I.F – 2.8). ISSN: 0944-1344 (Print) 1614-7499 (Online)
  • Balaji, A.P.B., Mishra, P., Kumar, R.S., Mukherjee, A. and Chandrasekaran, N., 2015. Nanoformulation of poly (ethylene glycol) polymerized organic insect repellent by PIT emulsification method and its application for Japanese encephalitis vector control. Colloids and Surfaces B: Biointerfaces, 128, pp.370-378. (I.F – 3.9). ISSN: 0927-7765
  • Balaji, A.P.B., Mishra, P., Kumar, R.S., Ashu, A., Margulis, K., Magdassi, S., Mukherjee, A. and Chandrasekaran, N., 2015. The environmentally benign form of pesticide in hydrodispersive nanometric form with improved efficacy against adult mosquitoes at low exposure concentrations. Bulletin of environmental contamination and toxicology, 95(6), pp.734-739. (I.F- 1.48). ISSN: 0007-4861 (print version) ,ISSN: 1432-0800 (electronic version)
  • Swathy, J.S., Mishra, P., Thomas, J., Mukherjee, A. and Chandrasekaran, N., 2018. Antimicrobial potency of high-energy emulsified black pepper oil nanoemulsion against aquaculture pathogen. Aquaculture, 491, pp.210-220. (I.F- 2.71). ISSN: 0044-8486
  • Swathy, J.S., Mishra, P., Thomas, J., Mukherjee, A. and Chandrasekaran, N., Nanometric neem oil emulsification through microfluidization, and its therapeutic potential against Aeromonas culicicola infection in Cyprinus carpio. Flavour and Fragrance Journal. (I.F- 1.95). ISSN:1099-1026
  • Swathy. J., S., Mishra, P., Mukherjee A., Chandrasekaran N., 2017. Comparative study between two different high-energy emulsification strategies for the preparation of bio- oil based nanoemulsion. Advance science letters. (In Press). ISSN: 1936-6612 (Print): EISSN: 1936-7317 (Online)
  • Book chapters :  Mishra P, A.P.B Balaji, Amitava Mukherjee, Natarajan Chandrasekaran.  Bio-based nanoemulsion: An eco-safe approach towards eco-toxicity problem. “Handbook of Eco- materials”.  In: Martínez LMT, Kharissova OV, Kharisov BI (Editors), Handbook of Ecomaterials. Springer International Publishing, Cham, pp. 1-23.
  • Book chapters :    Mishra P, A.P.B Balaji, Amitava Mukherjee, Natarajan Chandrasekaran. Nanopesticides: A  boon  towards  the  control  of  dreadful  vectors  of  lymphatic  filariasis.  “Lymphatic Filariasis”. Edited by Brij Kishore Tyagi. Springer Nature (In Press)

Thrust Areas of Research

Primary Research Areas includes:

  • Oncoimmunology
  • Inflammation
  • Disease Models
  • Neuro Biology
  • Physiology
  • Transgenic and RDT
  • Preclinical Biology
Research and Innovation
Office of Research and Innovation,
REVA University, Rukmini Knowledge Park Kattigenahalli, Yelahanka,
Bangalore – 560 064
Karnataka, India
+91-80-6622 6622
+91 9448809443

MOU with Industry/R&D organizations

    • Industry : 20 Companies (BIOCON, AURIGENE, HETERO DRUGS, VITAS PHARMA etc.)
    • R&D organizations : National Centers (CDFD-Hyderabad, NIANP-Bangalore, NIMHANS-Bangalore, RCB-New Delhi etc.)
    • International Collaborations : Mc Gill University-Montreal, CANADA, Michigan State University-East Lansing, USA